Back to Changelog
Feature

New Athena Vocabulary Release (v20260829)

Athena v20260829 is now the OMOPHub default, adding Mondo and ORPHAcode, expanded oncology mappings, refreshed terminologies, and verified semantic search.

The latest OHDSI Athena vocabulary release, v20260829, is now live on OMOPHub. It is available as vocabulary release 2026.2 and is the default for API requests that do not pin a release.

Release at a glance

Compared with the previous default, the source release contains:

2026.12026.2Change
Concept records10,005,29910,336,644+331,345
Vocabulary records130133+3
Concept-relationship records54,790,73054,946,134+155,404
Concept-synonym records5,172,3275,498,539+326,212
Concept-ancestor records85,049,81097,113,979+12,064,169

New rare-disease vocabularies

Two major public vocabularies join the release:

  • Mondo Disease Ontology: 27,753 concept records covering diseases and their relationships across multiple biomedical resources.
  • ORPHAcode: 6,191 concept rows for rare diseases and groups of rare diseases maintained by Orphanet.

HPO was also updated to its June 23, 2026 source release, adding 1,020 concept records since 2026.1.

Expanded oncology coverage

The OHDSI Oncology Working Group contributed a substantial cancer-vocabulary refresh:

  • 527 Cancer Modifier concepts added or revised.
  • 3,955 curated SNOMED and LOINC mapping rows.
  • 441 LOINC question-answer pairs for oncology findings.
  • 30 new standard OMOP Genomic concepts.
  • 581 new hierarchical relationships across Cancer Modifier and OMOP Genomic.

NAACCR was updated from version 18 to version 26, while LOINC moved from 2.80 to 2.82.

Core terminology updates

The release also refreshes frequently used clinical and drug vocabularies:

  • SNOMED CT International, US, and UK editions were updated to their 2026 releases.
  • RxNorm and RxNorm Extension were updated to June 2026 sources, including consolidation of more than 1,000 duplicate extension concepts.
  • ICD10CM and ICD10PCS moved to their 2027 source versions; ICD10GM moved to 2026.
  • NDC and SPL were updated through August 23, 2026.
  • HCPCS was updated to July 2026.
  • SNOMED Veterinary was updated to March 31, 2026.

The Nebraska Lexicon is now deprecated upstream. Its concepts were de-standardized and mapped to SNOMED equivalents, so applications using Nebraska Lexicon concepts should plan to migrate to SNOMED.

Accessing the new release

Requests without a release header now use 2026.2:

curl "https://api.omophub.com/v1/concepts/201826" \
  -H "Authorization: Bearer YOUR_API_KEY"

For reproducible pipelines, pin the release with X-Vocab-Release:

# Use the new release explicitly
curl "https://api.omophub.com/v1/concepts/201826" \
  -H "Authorization: Bearer YOUR_API_KEY" \
  -H "X-Vocab-Release: 2026.2"

# Keep using the previous release
curl "https://api.omophub.com/v1/concepts/201826" \
  -H "Authorization: Bearer YOUR_API_KEY" \
  -H "X-Vocab-Release: 2026.1"

Existing applications pinned to 2026.1 are unaffected by the default change.

Full Release notes

The detailed release notes can be found on GitHub

View all updates